Pulmonary toxicity, methotrexate and X-rays

Triboluminescence and X-Rays

Triboluminescence is shown to produce X-rays from the nanoparticles (NPs) that form as the sticky acrylic adhesive of Scotch tape is peeled from the polyethylene (PE) roll in a vacuum. Prior to peeling, atoms in the adhesive are not under electromagnetic (EM) confinement and have full thermal kT energy. But upon peeling, the atoms in NPs that form in the gap between adhesive and PE are under EM...

Subject headings: galaxies: general—galaxies: spiral—X-rays: general—X-rays: galaxies—X-rays: ISM

We present results from the analysis of deep ROSAT HRI and PSPC observations of the spiral galaxy M81. The inferred total (0.5–2 keV band) luminosity of M81 is ∼ 3×10 ergs s, excluding the contribution from identified interlopers found within the D25 ellipse. The nucleus of the galaxy alone accounts for about 65% of this luminosity. The rest is due to 26 other X-ray sources (contributing ∼ 10%)...

Methotrexate-induced pulmonary lymphoma.

Methotrexate has proven to be effective in treating rheumatoid arthritis (RA), and is believed to be nononcogenic in the low weekly dose typically employed in the patients with RA. We report, however, a patient with RA in whom a rapidly enlarging diffuse large B-cell lymphoma developed in the left upper lung after weekly treatment with methotrexate for 5 years. The patient had a positive serum ...

Polymorphisms within methotrexate pathway genes: Relationship between plasma methotrexate levels, toxicity experienced and outcome in pediatric acute lymphoblastic leukemia

Objective(s): The current study aimed to investigate the relationship of genetic polymorphism and plasma methotrexate (MTX) levels, toxicity experience and event free survival (EFS) in pediatric acute lymphoblastic leukemia (ALL). Materials and Methods: The study included 74 ALL patients. Polymerase chain reaction and genotyping of methy...

General Practice and X-Rays